Independence is a relatively large city located in the state of Missouri. With a population of 120,922 people and 36 associated neighborhoods, Independence is the fifth largest community in Missouri.

Also of interest is that Independence has more people living here who work in computers and math than 95% of the places in the US.

Telecommuters are a relatively large percentage of the workforce: 8.22% of people work from home. While this number may seem small overall, as a fraction of the total workforce it is high relative to the nation. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

The percentage of adults in Independence who are college-educated is close to the national average for all communities of 21.84%: 19.48% of the adults in Independence have a bachelor's degree or advanced degree.

The per capita income in Independence in 2022 was $31,491, which is upper middle income relative to Missouri, and middle income relative to the rest of the US. This equates to an annual income of $125,964 for a family of four. However, Independence contains both very wealthy and poor people as well.

Independence is a very ethnically-diverse city. The people who call Independence home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Independence residents report their race to be White, followed by Black or African-American. Important ancestries of people in Independence include German, Irish, English, European, and Italian.

The most common language spoken in Independence is English. Other important languages spoken here include Spanish and Pacific Island languages.